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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

VHL binds OTUD6B and cbc. 2 / 2

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sparser

"In this proposed model, OTUD6B is a direct transcriptional target of HIF‐1α, and HIF‐1α is a direct ubiquitylation and degradation target of OTUD6B‐CBC VHL complex."

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sparser

"We used gel filtration chromatography assay to analyze the CBC VHL complex binding of OTUD6B. As shown in Figure xref and Figure S5F (Supporting Information), OTUD6B was detected in the same fractions with pVHL, elongin B, and elongin C, indicating that OTUD6B might be a component of CBC VHL complex."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...