IndraLab

Statements

USP1 binds SHPRH. 5 / 5
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sparser
"In addition, we examined the importance of the TonEBP RHD, which encircles DNA and is essential for the interaction with SHPRH or USP1 ( xref A)."
31376680
sparser
"We hypothesized that TonEBP regulates PCNA ubiquitination in response to DNA damage by interacting with SHPRH and USP1."
31376680
sparser
"TonEBP was found to be recruited to DNA damage sites with bulky adducts and to regulate PCNA polyubiquitination through sequential interactions with SHPRH and USP1."
31376680
sparser
"In summary, TonEBP regulates DNA damage tolerance through sequential interactions with SHPRH and USP1."
31376680
sparser
"These results indicated that TonEBP regulates PCNA polyubiquitination through dynamic temporal interactions with SHPRH and USP1 in response to MMS treatment."
31376680