IndraLab

Statements

Oligonucleotide inhibits RELA. 4 / 4
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"Specifically, the NF- κ B p65 subunit seems to be an important regulator in intestinal inflammation in inflammatory bowel disease; in fact, treatment with antisense or decoy oligonucleotides that inhibit p65 has been shown to ameliorate the macroscopic signs of colitis as well as the nuclear accumulation and DNA binding activity of p65 protein in several models of intestinal inflammation [ xref – xref ]."
23346196
sparser
"Specifically, the NF- κ B p65 subunit seems to be an important regulator in intestinal inflammation in inflammatory bowel disease; in fact, treatment with antisense or decoy oligonucleotides that inhibit p65 has been shown to ameliorate the macroscopic signs of colitis as well as the nuclear accumulation and DNA binding activity of p65 protein in several models of intestinal inflammation [ xref – xref ]."
23346196
sparser
"Indeed, disease activity in mice with colitis is inhibited by antisense oligonucleotides that inhibit the p65 subunit of NF- κ B, which suggests a critical role for NF- κ B in mediating the inflammatory response [ xref ]."
26075036
sparser
"Indeed, disease activity in mice with colitis is inhibited by antisense oligonucleotides that inhibit the p65 subunit of NF- κ B, which suggests a critical role for NF- κ B in mediating the inflammatory response [ xref ]."
26075036