IndraLab

Statements


TP53 binds ELP2 and MDM2. 5 / 5
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sparser
"We found that the STIP-Mdm2 or STIP-p53 interactions were also significantly reduced (Figure xref )."

sparser
"STIP is associated with Mdm2 and p53 in vivo ."

sparser
"Furthermore, the STIP-Mdm2 or STIP-p53 interaction is likely to be direct, as shown by an in vitro pulldown assay with recombinant protein (Figure xref )."

sparser
"To further establish whether the association of STIP with Mdm2 and p53 occurs under natural conditions, reciprocal immunoprecipitation assays of endogenously expressed STIP proteins with anti-Mdm2 and anti-p53 antibodies were performed."

sparser
"Because STIP colocalizes and interacts with USP7 in vivo , we sought to determine whether STIP also associates with Mdm2 and p53."