IndraLab

Statements

CDK6 phosphorylates NPM1. 8 / 8
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"Moreover, K cyclin activates CDK6, which phosphorylates NPM1."
19326462
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"The v-Cyclin and CDK6 kinase also mediates phosphorylation of nucleophosmin (NPM) an indirect target of ATM, on threonine 199 in de novo and naturally KSHV infected cells."
27258263
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"The vCyclin and CDK6 complex also phosphorylates nucleophosmin (NPM), facilitating NPM-LANA interaction and recruitment of HDAC1 to regulate KSHV latency [XREF_BIBR]."
21625290
sparser
"The vCyclin-CDK6 complex also phosphorylates nucleophosmin (NPM), facilitating NPM-LANA interaction and recruitment of HDAC1 to regulate KSHV latency [ xref ]."
21625290
sparser
"Indeed, nucleophosmin can be phosphorylated by V-cyclin CDK6, and control the latency phase [ xref ]."
32377232
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"Additionally, v-Cyclin and CDK6 phosphorylation of NPM facilitates the interaction of LANA with the histone deacetylase HDAC1 to promote KSHV latency [XREF_BIBR]."
27258263
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"The exact role of this viral protein in regulating KSHV life cycle is not fully understood but studies indicate that v, Cyclin, and CDK6 complex mediated phosphorylation of nucleophosmin (NPM) facilitates NPM-LANA interaction and recruitment of HDAC1 to promote KSHV latency [XREF_BIBR]."
25594667
sparser
"Moreover, K cyclin activates CDK6, which phosphorylates NPM1."
19326462