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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

WT1 bound to SWI_SNF inhibits WT1. 1 / 1

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reach

"Tbeta4 knockout mice, followed by MI, revealed a modest increase in SWI/SNF binding Wt1 ECRs and associated increase in Wt1 expression during heart injury (XREF_FIG; also in development, XREF_SUPPLEMENTARY), however, priming with exogenous Tbeta4 in Tbeta4 knockout mice, followed by MI, resulted in significantly enhanced binding of the SWI and SNF complex to Wt1 ECRs augmenting Wt1 reactivation (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...