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phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach

VEGFR binds DUSP1, EGF, EGFR, and F2R. 1 / 1
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"In a study on endothelial cells (ECs) Chandrasekharan and colleagues provided an interesting example for a complex metalloproteinase-independent, but EGF-dependent signalling interaction between PAR 1 , the EGFR and the VEGFR, resulting in transcriptional activation by mitogen-activated protein kinase phosphatase 1 (MKP-1), a key signalling mediator in thrombin and VEGF-mediated activation of endothelial cells."