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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

USP18 leads to the deubiquitination of K285/309R on K63. 1 / 1

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"To further clarify this point, we constructed NEMO double mutants NEMO (K325/326R) and NEMO (K285/309R) (as control) and found USP18 inhibited K63 linked ubiquitination of the NEMO (WT) and NEMO (K285/309R) constructs, but not the NEMO (K325/326R) mutant (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...