IndraLab

Statements


SCN8A inhibits LYST. 5 / 5
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"Kelly and colleagues found that in types I/II people 0.25 MED suppressed CHS by 50% and 0.50 MED suppressed it by 80%, whereas in types III/IV people 1 MED suppressed CHS by 40%."

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"Kelly and colleagues found that in types I/II people 0.25 MED suppressed CHS by 50% and 0.50 MED suppressed it by 80%, whereas in types III/IV people 1 MED suppressed CHS by 40%."

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"However, a single suberythemal exposure of either 0.25 or 0.5 MED suppressed CHS responses by 50 and 80%, respectively, in skin types I/II, whereas 1 MED only suppressed CHS by 40% in skin types III/IV."

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"A moderate but vivid sunburn (2 MED) completely suppressed CHS (93%) in all volunteers regardless of skin type, but skin types I/II were more sensitive to suberythemal exposure."

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"Not only did low-dose UVR suppress local CHS responses, but our previous studies showed that 3 MED SSR suppressed CHS responses by 93% (12/12 volunteers) when sensitizer was applied to irradiated skin and also suppressed CHS responses by the same amount (10/12 volunteers) when sensitizer was applied at a distant site 24 h after irradiation 10."