IndraLab

Statements


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sparser
"This increased association of LRP6 and Wnt11 in embryos over-expressing XtSulf1 is consistent with the increased axes-inducing activity of Wnt11 mRNA when co-injected with XtSulf1 ."

reach
"This could explain the observation that leupeptin caused decreased interaction between Wnt5a or Wnt11 and LRP6."

reach
"The LRP6 (P1104S) mutation did n't affect the interaction with CTSD, but it could inhibit the interaction of Wnt5a or Wnt11 and LRP6, blocking the degradation of Wnt5a or Wnt11 by CTSD and resulting in pathological cardiac remodeling."

sparser
"We therefore investigated if XtSulf1 can influence the association of Wnt11 and LRP6."