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PTEN decreases the amount of USP13. 1 / 1

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"Expression of USP13 (but not the C345A mutant) in MDA-MB-231 cells, which led to upregulation of PTEN and downregulation of phospho-AKT and phospho-FOXO1/3 (XREF_FIG), significantly inhibited cell proliferation (XREF_FIG), colony formation on soft agar (XREF_FIG), lactate production (XREF_FIG), glucose uptake (XREF_FIG) and tumor growth (XREF_FIG), while knockdown of PTEN (XREF_SUPPLEMENTARY) rescued the proliferation of USP13 overexpressing MDA-MB-231 cells (XREF_FIG)."

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PTEN decreases the amount of USP13. 1 / 1

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