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EMMAA Bob with Bioagents

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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

OTUD1 inhibits EAF2. 5 / 5

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"These results suggest that OTUD1 reduces the manifestation of cancer stem cell traits."

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"Combined, the in vitro and in vivo evidence in this study elucidates critical functions of OTUD1 in the termination of TGF-beta and SMAD-induced metastatic activation, indicating that OTUD1 restricts the EMT and cancer stem cell traits during metastasis."

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"OTUD1 inhibits cancer stem cell traits."

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"OTUD1 inhibits cancer stem cell traits."

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"From our screen, we have identified that loss of OTUD1 enables breast cancer cells to undergo EMT and gain cancer stem cell traits thereby driving metastatic spread to distant organs, such as bone and lung."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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