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STAT3 bound to PIAS3 is inactive. 1 / 1

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"PIAS3 blocked the DNA- binding activity of Stat3 and inhibited Stat3-mediated gene activation. Although Stat1 is also phosphorylated in response to IL-6, PIAS3 did not interact with Stat1 or affect its DNA-binding or transcriptional activity. The results indicate that PIAS3 is a specific inhibitor of Stat3."

9388184

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IndraLab

Statements

STAT3 bound to PIAS3 is inactive. 1 / 1

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