IndraLab

Statements

CDKN2B methylates CDKN2A. 5 / 5
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reach
"Accumulating evidence suggests an almost universal inactivation of the RB pathway in HCC, including by promoter hypermethylation of the p16 INK4a (~ 50% of cases) or p15 INK4b (~ 15% of cases) genes, and amplification of the gene coding for Cyclin D1 (~ 30% of cases)."
21875955
sparser
"Their results indicated that the rates ofp15 INK4B andp16 INK4A promoter methylation in MM samples were significantly higher compared with normal controls."
25382971
reach
"In RRP Case 5, aberrant methylation of BRAC2, APC and CDKN2A in the reference papilloma biopsy and CDKN2B in biopsy 2 were also identified in the subsequent progression lesions (XREF_TABLE)."
22388100
reach
"In RRP Case 5, aberrant methylation of BRAC2, APC and CDKN2A in the reference papilloma biopsy and CDKN2B in biopsy 2 were also identified in the subsequent progression lesions (XREF_TABLE, XREF_FIG)."
21603083
sparser
"Another intriguing observation in our study was the positive significant correlation between ANRIL exon 1–5 expression andp15 INK4b andp16 INK4a methylation (r = 0.23, p = 0.001 and r = 0.24, p = 0.001, respectively)."
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