IndraLab

Statements


Beta1 subunit inhibits KCNMA1. 2 / 2
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"Similarly to BKalpha subunit knockout, beta1 subunit ablation reduces BK channel activity in arterial myocytes, elevates arterial contractility and increases systemic blood pressure."

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"The observation in XREF_FIG E that the beta1 subunit decreases the voltage sensitivity of Slo1 core and Slo3 tail channels, shifting V 0.5 10-20 mV positive (XREF_FIG F), suggests that the beta1 subunit is expressed and that it does associate in some manner with the Slo1 core and Slo3 tail channels."