IndraLab

Statements

SOS1 binds GRB2 and SH3 domains. 3 / 3
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"It is thus conceivable that the SH3 domains of Grb2 bind to Sos1 simultaneously and thereby leading to enhancement of Grb2-Sos1 interaction.In short, our data reported here provide key insights into t[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
18778683
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"Understanding the biological functions of mammalian Grb2 is complicated by the finding that the Grb2 SH3 domains potentially bind a number of protein ligands in addition to Sos1 and Sos2."
9865697
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"Subsequently, two SH3 domains of GRB2 bind the proline rich SOS1 C-terminal tail (52-55), recruiting SOS1 to the cell membrane."
30097175