Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

HACE1-S385E ubiquitinates RAC1. 2 / 2

| 2

➶

reach

"In good agreement with our findings that HACE1 (S385E) retains its catalytic activity, we also determined that HACE1 (S385E) induces the ubiquitination of recombinant Rac1 loaded with GTPgammaS in vitro."

29362425

➶

reach

"Thus, the reduced capacity of HACE1 (S385E) to ubiquitinate active Rac1 is not due to a reduced association with its target but might instead be explained by a modulation of its enzymatic activity."

29362425

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...