IndraLab

Statements


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"AML1 is a member of a family of transcription factors with homology to the Drosophila pair-rule gene runt and directly binds the enhancer core DNA sequence TGT and cGGT, which is present in a number o[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Under physiologic conditions, the N-terminus of RUNX1 interacts with the CBFB subunit and binds the consensus sequence TGT and cGGT at the promoter regions of its target genes [XREF_BIBR]."

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"These results demonstrate that AML1 and ETO binds to an AML1 consensus sequence TGT and cGGY on survivin promotor."

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"AML1 binds to the consensus DNA sequence TGT and cGGT, which is present in a number of promoters and enhancers of viral and cellular genes, through its Runt domain."

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"In normal cells, RUNX1 bound to the enhancer sequence TGT and CGGT whereas MTG8 is a transcriptional repressor able to interact with other co-repressors."