IndraLab

Statements


CD8 inhibits CYLD. 2 / 2
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"However, the parasite load in the CD8 + T cell depleted Cyld -/- mice was always lower compared to CD8 + T cell depleted WT mice, indicating that in addition to the contribution of CD8 + T cells the enhanced parasite control in the Cyld -/- mice is also mediated by other cell types, likely Cyld -/- macrophages and granulocytes."

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"Although our CD8 + T cell depletion experiments show the importance of CD8 + T cells in the control of PbA blood parasites, CD8 + T cell depleted Cyld -/- mice harbored lower parasite loads compared to CD8 + T cell depleted WT mice, indicating that the enhanced parasite control in the Cyld -/- mice is also mediated by other immune cells in addition to CD8 + T cells."