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USP1 activates PC cell. 1 / 1
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eidos
"The supportive evidence is as follows : ( i ) USP1 knockdown decreased PC cell proliferation in vitro and tumorigenesis in vivo , and promoted the response to therapeutic agent enzalutamide ; and ( ii ) inhibition of USP1 sensitized cancer cells to therapeutic agent enzalutamide , whereas this effect was blunted by overexpression of KDM4A ."