IndraLab

Statements


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reach
"As expected, OTULIN treatment abolished the detection of ubiquitin chains (Fig XREF_FIG A, top panel), confirming that linear ubiquitination occurs in adult flies."

reach
"In this study, the ‘deubiquitinase’ OTULIN was shown to restrict bacterial growth by controlling the density of linear ubiquitin chains on the bacterial surface, which serves as a platform for NF-κB activation.Finally, lattice light-sheet microscopy (LLSM) is a newly developed super-resolution microscopy method, which capitalises on previous microscopy techniques (light-sheet microscopy, SIM) and provides gentle and fast super-resolution in a volumetric sample13."

reach
"In this study, the ‘deubiquitinase’ OTULIN was shown to restrict bacterial growth by controlling the density of linear ubiquitin chains on the bacterial surface, which serves as a platform for NF-κB activation.Finally, lattice light-sheet microscopy (LLSM) is a newly developed super-resolution microscopy method, which capitalises on previous microscopy techniques (light-sheet microscopy, SIM) and provides gentle and fast super-resolution in a volumetric sample ."

reach
"OTULIN prevents such promiscuity by requiring a properly positioned Ub residue, Glu16, for catalytic efficiency."