IndraLab
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"Results Pol iota is a substrate and interacting partner of USP7 The monoubiquitination of Pol iota is dependent on its ubiquitin-binding motifs ( UBMs ) and their capacity to bind and recruit ubiquitin-laden E2 enzymes.26 ,28 While these domains are major drivers of Pol iota monoubiquitination , we considered whether additional regulation of Pol iota ubiquitination might also be mediated by DUBs ."