IndraLab

Statements

CDK1 phosphorylates NPM1 on T234. 10 / 10
1 3 3 1 | 2
reach
"CDK1 phosphorylation of NPM at threonine 234/237 is critical in HCC migration and invasion."
26536659
phosphoelm
No evidence text available
14670079
signor
"CDK1-cyclin B phosphorylates NPM/B23 on Thr234."
11278991
biopax:phosphositeplus
No evidence text available
hprd
No evidence text available
11278991
hprd
No evidence text available
20068231
signor
"Both subtypes of B23 proteins were phosphorylated during mitosis by cyclin B/cdc2. The RNA binding activity of B23.1 was repressed through cyclin B/cdc2-mediated phosphorylation at specific sites in B23. Thus, the RNA binding activity of B23.1 is stringently modulated by its phosphorylation and subtype association."
12058066
hprd
No evidence text available
17287340
reach
"10 CDK1 phosphorylates NPM at the beginning of mitosis at Thr199 and Thr234/237, resulting in inhibition of NPM RNA binding activity."
25908633
signor
"We have recently found that nucleophosmin (npm/b23), a phosphoprotein primarily found in nucleolus, associates with unduplicated centrosomes and is a direct substrate of cdk2-cyclin e in centrosome duplication."
14670079