IndraLab

Statements

CALM binds CALM1. 16 / 16
| 16
sparser
"Binding of uranyl to the unphosphorylated CaM-WT and CaM1 peptides was characterized by conditional dissociation constants in the nanomolar range (K d  = 32±7 and 25±6 nM, respectively)."
22870263
sparser
"The CaM1, CaM4, CaM5, CaM6 and CaM7 interacts with MPK8 ( xref )."
30909616
sparser
"These results suggest that in vitro binding of TCF4B and CaM or CaM1,2,3,4 can occur independently of Ca 2+ binding, but that in vivo CaM-dependent prevention of pyramidal cell aggregation by TCF4B gain of function requires Ca 2+ , because the Ca 2+ insensitive CaM1,2,3,4 was ineffective at rescuing cellular aggregation."
28289282
sparser
"The CNGB1 mutation F575E abolishes CaM1 binding to the CaM N-lobe while L1132E and L1136E each abolish CaM2 binding to the CaM C-lobe."
36070238
sparser
"These same resonances are exchange broadened in CaM bound to the CNGB1 CaM1 peptide (Bej and Ames xref ) and the α-subunit of the retinal cyclic nucleotide-gated channel (CNGA2) (Contessa et al. xref ), but are not exchange broadened in free CaM (Bej and Ames xref ; Kainosho et al. xref )."
35986879
sparser
"The interaction of CAM1 with CaM depends on the Ca2+ occupancy of its Ca(2+)-binding sites."
10076799
sparser
"It was shown that GAD activity is induced by two different mechanisms: (i) in intact plant tissue and neutral pH GAD activity is stimulated in a Ca 2+ -dependent manner by binding of calmodulin to the CAM-binding site ( xref ); (ii) after wounding of plant cells the vacuolar content is released and the cytosol is acidified which leads to a Ca 2+ -independent activation of GADs ( xref )."
28382046
sparser
"Our binding studies reveal that CaM1 binds to the Ca 2+ -bound CaM N-lobe with at least fivefold higher affinity than it binds to the CaM C-lobe."
36070238
sparser
"To determine if Ca 2+ was necessary for binding of CaM or CaM1,2,3,4 to TCF4B in vitro , we altered the Ca 2+ concentration in our protein lysates and performed additional co-immunoprecipitation experiments."
28289282
sparser
"We present separate NMR structures of Ca 2+ -saturated CaM bound to CaM1 and CaM2 that define key intermolecular contacts: CaM1 residue F575 interacts with the CaM N-lobe while CaM2 residues L1129, L1132, and L1136 each make close contact with the CaM C-lobe."
36070238
sparser
"The PDE1 activation process involves Ca 2+ binding to the free CaM region, which results in the activation of the Ca 2+ -CAM and changes in the conformation of the PDE1 structure (Ca 2+ -CaM*-PDE1)."
33153226
sparser
"Biosensor experiments were performed to determine rate and equilibrium constants of the C-CAM/calmodulin interaction."
8576129
sparser
"Increase of the calcium concentration leads to calmodulin binding to C-CAM; this binding causes dissociation of C-CAM dimers."
9330864
sparser
"Binding of calmodulin to C-CAM is regulated by the intracellular calcium concentration and leads to downregulation of C-CAM self-association [74°]."
9330864
sparser
"Among seven calmodulins (CaM1–CaM7), JAV1 strongly interacts with CaM1, CaM4, and CaM7 ( A, A, and S2B)."
29625034
sparser
"These data indicate that the effect of calmodulin binding to RYR CaM1 may be regulated by the phosphorylation state of the Ser residue localized within the sequence Arg-His-Arg-Val(Ile)-Ser-Leu."
7711031