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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

PP1beta leads to the phosphorylation of NPM1. 2 / 2

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"Among the three isoforms, depletion of PP1beta caused dramatic NPM hyperphosphorylation, whereas PP1alpha and -gamma knockdown had little effect on the basal phosphorylation level (XREF_FIG B and its shorter exposed version in Supplemental Figure S3B)."

20962268

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"Consistently, upon siRNA mediated reduction of intracellular PP1beta, which was shown to increase the phosphorylation of NPM (XREF_FIG B), a loss of interaction between NPM and pRB was observed (XREF_FIG E)."

20962268

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...