IndraLab

Statements



reach
"Our results reveal that USP33 acts as the deubiquitinating enzyme of SP1 and contributes to HCC invasion and metastasis through activation of the SP1 and c-Met axis."

reach
"We found that USP33 knockdown inhibited the invasion and metastasis in HCC cells both in vitro and in vivo, which was partly dependent on c-Met."

eidos
"Our results reveal that USP33 acts as the deubiquitinating enzyme of SP1 and contributes to HCC invasion and metastasis through activation of the SP1 / c-Met axis ."

reach
"Secondly, the details of mechanisms by which USP33 promotes GAC growth and metastasis are still unclear; for example, the effects of USP33 on cell viability may be caused by either suppressing proliferation or enhancing apoptosis."

reach
"In conclusion, our study found that USP33 contributed to the proliferation and metastasis of pancreatic cancer through a positive feedback loop with TGF-β signaling pathway."