IndraLab

Statements


KCNMA1 activates p38. 9 / 9
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"SLO activated p38 in these cells, indicating that this event was also independent of TLR4 ( Fig. 4 )."

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"S. pyogenes SLO perforates human PMNs and induces Ca 2+ influx and p38 MAPK activation, consequently inducing HBP release XREF_BIBR."

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"SLO activated p38 in these cells, indicating that this event was also independent of TLR4 ( Fig. 4 )."

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"In mast-cells, low doses of SLO or listeriolysin (LLO) activates the MAPK p38 pathway resulting in up regulation of cytokines mRNA expression such as tumor necrosis factor alpha (TNF-alpha)."

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"While streptolysin O (SLO) reportedly activates p38 MAPK via reactive oxygen species (ROS), we showed that this pathway did not play a major role in p38 phosphorylation in beta-toxin-treated cells."

sparser
"It was found that [K + ]-hi medium also attenuated p38-activation by HlyA or SLO ( Fig. 3 C–D)."

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"Activation of p38 by SLO, PLY, ALO, and VLY leads to IL-8 production [ xref , xref , xref ]."

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"Like HlyA, wild type SLO activated p38 in CD14-deficient A498 cells ( Fig. 4 D)."

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"It was also reported that activation of p38 by PFT is non dependent of TLR4 immune receptor since HlyA or SLO toxins are sufficient to activate p38 in epithelial cells or human embryonic kidney cells (HEK-293) lacking CD14, a coreceptor of TLR4 [XREF_BIBR]."