IndraLab
Statements
reach
"As shown in XREF_FIG, NFKBIA knockdown completely or partially rescued KLF6-wt effect on the majority of the tested genes; furthermore, although not always statistically significant, it seemed to prevent KLF6 mediated upregulation of the other NF-kappaB-negative regulators (TNIP1, TNIP2 and TNFAIP3, XREF_SUPPLEMENTARY), suggesting that NF-kappaB could mediate a positive feedback loop by downregulating its negative regulators as previously described."