IndraLab

Statements


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"These observations raise the question as to what kind of agents could be utilized in an attempt to block migration of leukemic blasts in a therapeutic manner during induction therapy, and the candidat[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Identifying the mechanisms by which CAMS, individually and in combination, initiate cellular interactions that alter tissue morphology [5] is a major challenge, as are the delineations of the signal p[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In this way, a cell is able to control CAM mediated adhesion in response to external stimuli (see also Update)."

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"If on the other hand a particular CAM mediates cell to cell adhesion and cells aggregate, they may become more mobile and protected from cytotoxicity."

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"The most provocative, however, are those that indicate that CAM mediated adhesion may lead to changes in gene expression and those that suggest that the expression of CAM genes may be regulated by the[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"We found, as has also been described by others [21,22], that C- CAM 1 could mediate adhesion in vitro."

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"Nevertheless, it is clear that CAM mediated adhesion can have a significant effect on cell behavior."

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"The use of transfection to express CAMS in cells that normally do not express them also indicated that CAMS can influence a variety of cell parameters and provided some hint that CAM mediated adhesion[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Integrins are a basal and principal CAM that mediate cell adhesion to make solid tumor cells grow in three-dimensional architectures, and integrins are widely expressed in almost all cancer cells orig[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"However, the application of anti-CAM Fab to retinal cells cultured through to neurite formation [36], to the outgrowth ofneurites from spinal ganglion cultures [38] and to isolated embryonic retina in[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"It 's worth mentioning that CAM could mediate the adhesion of cancer cells and extracellular matrix [9,10]."

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"To examine the function of axoglial CAMs, we tested whether enhanced CAM mediated adhesion between OLs and neurons could affect myelination."