IndraLab

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CALM1 activates cell adhesion. 16 / 16
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"At least eleven at : subunits can combine with seven / 3 subunits to yield at Ieast 16 heterodimers and these numbers are still increasing.The Leu Cam ieucocyte receptors also belong to this superfamily and mediate adhesion of polymorphonuclears, monocytes and lymphocytes to each other and to a complement component, C3bi 1841."
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"The various studies listed above [28-31] showed that such CAM, when expressed in cells lacking CAM activity, can lead to shape changes and specific cell adhesion."
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"It is commonly believed that the transendothelial migration of the lymphocyte is governed by the intracellular domain of ICAM-1 ( Millan et al., 2006 ) and by the coordinated expression of adhesion mo[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"However, the application of anti-CAM Fab to retinal cells cultured through to neurite formation [36], to the outgrowth ofneurites from spinal ganglion cultures [38] and to isolated embryonic retina in[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"If on the other hand a particular CAM mediates cell to cell adhesion and cells aggregate, they may become more mobile and protected from cytotoxicity."
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"It 's worth mentioning that CAM could mediate the adhesion of cancer cells and extracellular matrix [9,10]."
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"To examine the function of axoglial CAMs, we tested whether enhanced CAM mediated adhesion between OLs and neurons could affect myelination."
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"These observations raise the question as to what kind of agents could be utilized in an attempt to block migration of leukemic blasts in a therapeutic manner during induction therapy, and the candidat[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Integrins are a basal and principal CAM that mediate cell adhesion to make solid tumor cells grow in three-dimensional architectures, and integrins are widely expressed in almost all cancer cells orig[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"We found, as has also been described by others [21,22], that C- CAM 1 could mediate adhesion in vitro."
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"The most provocative, however, are those that indicate that CAM mediated adhesion may lead to changes in gene expression and those that suggest that the expression of CAM genes may be regulated by the[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In this way, a cell is able to control CAM mediated adhesion in response to external stimuli (see also Update)."
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"Nevertheless, it is clear that CAM mediated adhesion can have a significant effect on cell behavior."
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"The use of transfection to express CAMS in cells that normally do not express them also indicated that CAMS can influence a variety of cell parameters and provided some hint that CAM mediated adhesion[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Mutations that abolish the ability of E-cadherin to interact with p120 result in the failure of this CAM to promote strong cell adhesion (Thoreson et al. 2000)."
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"Identifying the mechanisms by which CAMS, individually and in combination, initiate cellular interactions that alter tissue morphology [5] is a major challenge, as are the delineations of the signal p[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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