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USP2 inhibits calcium(2+). 3 / 3
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"Altogether, we initially demonstrated that USP2 overexpression suppressed hypertrophy, calcium overload, and mitochondrial dysfunction and increased protein levels of MFN2 via deubiquitination in Ang [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Our subsequent results revealed that Ang II induced increases in Ca 2+ content and expression levels of calcium overload-related protein t-CaMKⅡ, and p-CaMKⅡ and a reduction in SERCA2 expression, wher[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In summary, we found that the inactivation of Usp2 in mouse and of its orthologue CG14619 in Drosophila does not affect the circadian free running period, but impairs bodily Ca 2+ homeostasis in both species, especially in dietary Ca 2+ absorption in mouse small intestine."
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