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CALM1 binds AQP. 6 / 6
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"CAM binding to MIP was determined by the gel overlay assay described by Louis et al. [18,19]."
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"As expected, there was a significant decrease in CAM binding to MIP in 90th day diabetic lenses compared to controls (compare lane 2 with lane 1, Fig. 4B)."
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"This study shows that CAM binding to MIP is decreased in diabetic lenses."
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"Since CAM is a ubiquitous Ca 2+ binding protein, decreased CAM binding to MIP is likely to affect Ca 2+ -mediated cellular processes, including water permeability, and thus affecting lens fiber cell h[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"As shown in Fig. 3A, in vitro glycation decreased CAM binding to MIP."
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"However, our results show a decreased binding of CAM to MIP in diabetic lenses (Figs. 3 and 4), which is associated with decreased water permeability [31]."
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