IndraLab

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"Moreover, we found interaction between Bax and USP30, as well as aumdubin-increased ubiquitination and mitochondrial location of Bax."

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"As shown in Fig. 6A, B, endogenous USP30, but not other DUBs such as proteasomal USP14 and mitochondrial USP15, was detected in the Bax affinity-isolation precipitates of A549 and H1299 cells, indicating that USP30 can specifically bind with Bax."