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ZUP1 inhibits MAVS. 2 / 2
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"This enabled us, for the first time, to demonstrate that the DUB activity of MERS-CoV PL pro can suppress the MAVS-mediated induction of IFN-␤ expression.Cells, Antibodies, and Plasmids-HEK293T cells were cultured in Dulbecco's modified Eagle's medium (DMEM) supplemented with 10% fetal calf serum (FCS; Bodinco BV), 100 units/ml penicillin, 100 units/ml streptomycin, and 2 mM L-glutamine (cell culture medium and supplements were obtained from Lonza)."

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"Thisenabled us, for the first time, to demonstrate that the DUB activity of MERS-CoVPLpro can suppress the MAVS-mediated induction of IFN-βexpression.HEK293T cells were cultured in Dulbecco's modified Eagle's medium (DMEM)supplemented with 10% fetal calf serum (FCS; Bodinco BV), 100 units/mlpenicillin, 100 units/ml streptomycin, and 2 mml-glutamine (cell culture medium and supplements were obtainedfrom Lonza)."