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KCNH3 binds ced-9. 7 / 7
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"Furthermore, BEC-1 forms a complex with the antiapoptotic protein CED-9 and Bcl-2, and its depletion triggers CED-3 and Caspase-dependent PCD."
16111945
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"Because this regulatory mechanism is probably evolutionary conserved in C. elegans [ xref , xref ], it could be the case that DAPK-1 modulates autophagy by regulating the interaction between BEC-1 and CED-9 in C. elegans ."
19878311
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"Because this regulatory mechanism is probably evolutionary conserved in C. elegans [XREF_BIBR, XREF_BIBR], it could be the case that DAPK-1 modulates autophagy by regulating the interaction between BEC-1 and CED-9 in C. elegans."
19878311
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"The interaction between Beclin-1 and pro survival Bcl-2, used to inhibit autophagy, is conserved in the nematode model, with BEC-1 and CED-9 protein interactions disrupting the formation of the Beclin-1 initiation complex."
20087441
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"It is possible that DAPK-1 and JNK-1 modulate autophagy by regulating the interaction between BEC-1 and CED-9 in a tissue-specific manner."
19878311
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"Thus, EGL-1 might not only positively regulate programmed cell death, but might also positively regulate autophagy by interacting with CED-9 to induce BEC-1 release from CED-9 and BEC-1 complexes."
18567846
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"It is possible that DAPK-1 and JNK-1 modulate autophagy by regulating the interaction between BEC-1 and CED-9 in a tissue specific manner."
19878311