IndraLab

Statements


7 1 | 7

sparser
"Support for the fact that the two proteins occupy the same binding site came from the observation that UIP1 blocked the interaction between UCH37 and S14 in vitro [ xref ]."

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sparser
"The results of the yeast two-hybrid assay indicates that S14 may interact with UCH37 and that the interaction may be dependent on both the N-terminal UCH domain and the C-terminal extension of UCH37."

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sparser
"As the results of experiments using the yeast two-hybrid assay showed that the interaction between UIP1 and UCH37 was much stronger than that between S14 and UCH37, it was therefore of interest to det[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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sparser
"This indicates that UCH37 binds UIP1 preferentially and that the binding of S14 by UCH37 may be blocked by UIP1."

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sparser
"The interaction of UCH37 with S14 was further confirmed by an in vitro binding assay."

sparser
"The finding of the interaction between S14 and UCH37 may provide insights into the subunit arrangement of PA700, in particular the subunits of PA700 that associate with UCH37."

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sparser
"This suggests that UIP1 may modulate UCH37’s interaction with S14 in the 26S proteasome."

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