IndraLab

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COPS5 activates MIF. 5 / 8
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"Bucala suggests that higher MIF concentrations, that are typically associated with some of the enzymatic activities of MIF and its direct stimulation of TNF and NO in macrophages, could be responsible[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
11932196
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"The sustained ERK activation induced by MIF was suggested to be mediated by autocrine MIF, and Rho GTPase, MLCK activation may be involved in this process XREF_BIBR, XREF_BIBR, while Jab1 inhibits the sustained ERK activation likely by blocking MIF secretion XREF_BIBR, XREF_BIBR."
21283538
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"Subsequent degradation may occur through JAB 's COP9 signalosome associated role in ubiquitin-E3 ligase-26 S proteasome mediated protein degradation.On the other hand, our siRNA experiments clearly in[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
16122907
eidos
"In addition , network analysis demonstrates that insulin receptor substrate 1 can ameliorate amyloid-beta protein precursor through COP9 signalosome complex subunit 5 that enhances MIF elevation ."
35754265
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"In addition, network analysis demonstrates that insulin receptor substrate 1 can ameliorate amyloid-β protein precursor through COP9 signalosome complex subunit 5 that enhances MIF elevation."
35754265