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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

Phosphorylated CHEK2 phosphorylates TP53. 3 / 3

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"The phosphorylated CHK2 then phosphorylates p53 and CDC25."

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"Furthermore, phosphorylation of checkpoint kinases CHK1 and CHK2 promotes the phosphorylation of p53 and enhances the stability of p53, hence causing activation of CASP3."

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"The phosphorylated CHK2 then phosphorylates p53 and CDC25."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

Phosphorylated CHEK2 phosphorylates TP53. 3 / 3

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