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USP11 inhibits resistance poly ADP-ribose polymerase PARP1 Ubiquitination tumor metabolism regulation Ubiquitination mTORC1 signaling pathway. 1 / 1
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"USP11 is often overexpressed in cancer and induces resistance to poly ( ADP-ribose ) polymerase 1 ( PARP1 ) inhibitors.124 Ubiquitination in tumor metabolism regulation Ubiquitination in the mTORC1 signaling pathway As an important nutrient and key environmental stimulus , amino acids play a critical role in the mechanistic target of rapamycin complex 1 ( mTORC1 ) signaling pathway ."