IndraLab

Statements


IKK_complex ubiquitinates CYLD. 3 / 3
| 3

reach
"Together, these results demonstrate that IKK mediated phosphorylation of Ser432 and Ser436 might play a pivotal role in triggering SCF beta-TRCP -dependent CYLD poly-ubiquitination."

reach
"Here, we report that SCF beta-TRCP regulates the ubiquitination and degradation of CYLD, a process dependent on prior phosphorylation of CYLD at Ser432 and Ser436 by IKK."

reach
"IKK promotes CYLD ubiquitination and subsequent degradation."