IndraLab

Statements

Modified STAT3 increases the amount of MMP9. 3 / 3
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"A number of studies have demonstrated that the expression of activated STAT3 modulated metastasis of tumor cells by promoting gene transcription of MMP2 and MMP9."
29541181
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"Stable expression of active STAT3 increased matrix metalloproteinase MMP-9 mRNA levels in MCF-7 cells, indicating that it too is regulated by STAT3."
26559373
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"Constructive expression of STAT3 can up-regulate the expression of MMP-2 and MMP-9, which are able to efficiently degrade the extracellular matrix and basement membrane, promoting invasion and metastasis of cancer cells."
22179587