IndraLab

Statements

TAZ binds USP1. 9 / 9
| 2 7
sparser
"In breast cancers, the deubiquitinase USP1 can interact with TAZ to cause increased protein stability [ xref ]."
33557087
sparser
"The phosphodegron present in the N-terminal region facilitates interaction with the SCF β-TrCP complex, so, the interaction of TAZ and USP1 in this location may block interaction with other proteins, resulting in the increase of the TAZ protein expression observed with our findings."
33114077
sparser
"To determine whether USP1 interacts with TAZ, we co-transfected Flag-TAZ and HA-USP1 into HEK293T cells and co-immunoprecipitation (co-IP) assays were performed."
33114077
sparser
"We demonstrated that USP1 interacts with TAZ and increases TAZ protein stability."
33114077
reach
"In breast cancers, the deubiquitinase USP1 can interact with TAZ to cause increased protein stability [XREF_BIBR]."
33557087
sparser
"Furthermore, we confirmed that both exogenous TAZ or USP1 can interact with endogenous USP1 or TAZ ( xref B)."
33114077
reach
"We demonstrated that USP1 interacts with TAZ and increases TAZ protein stability."
33114077
sparser
"We found that USP1 interacts with TAZ and loss of USP1 reduces cell proliferation in a partially TAZ-dependent manner."
33114077
sparser
"Further characterization of USP1 and TAZ interaction at the amino acid level may provide further insight into TAZ cytoplasmic and nuclear shuttling."
33114077