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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

GTP-bound active HRAS increases the amount of CDKN1A. 1 / 1

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"H-RasG12V expression down-regulated p27Kip1 expression, and that RASSF1A co-transfected with H-RasG12V recovered p27Kip1 expression that had been down-regulated by H-RasG12V expression. Similarly, p21WAF1/CIP1 was induced by H-RasG12V expression and RASSF1A co-transfected with H-RasG12V inhibited p21WAF1/CIP1 induction."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...