IndraLab

Statements

USP10 binds ZC3H12A. 9 / 10
3 | 4 2
sparser
"They found that MCPIP1 directly binds to USP10 and serves as a bridge between USP10 and TANK [33] ."
35627217
biogrid
No evidence text available
24270572
biogrid
No evidence text available
25861989
sparser
"MCPIP1 associated with USP10 (Ubiquitin Specific Peptidase 10) after genotoxic stress, enhancing the latter’s deubiquitinase activity, thereby producing deubiquitination of NEMO (IKK-γ) which resulted in inhibition of NF-κB activation ( xref )."
26399696
reach
"They found that MCPIP1 directly binds to USP10 and serves as a bridge between USP10 and TANK [33]."
35627217
biogrid
No evidence text available
24270572
reach
"Altogether, these data support that TANK may also serve as a negative regulator of genotoxic NF-kappaB activation by directing USP10 and MCPIP1 complex to polyubiquitinated TRAF6."
28626800
reach
"MCPIP1 associated with USP10 (Ubiquitin Specific Peptidase 10) after genotoxic stress, enhancing the latter 's deubiquitinase activity, thereby producing deubiquitination of NEMO (IKK-gamma) which resulted in inhibition of NF-kappaB activation."
26399696
reach
"MCPIP1 forms a complex with USP10 and TANK, which mediates the deubiquitination of the TRAF6 K63 chain [76] and inhibits NF-κB activation upon DNA damage [33]."
35627217