IndraLab
Statements
eidos
"Taken together , these results reveal that upregulation of USP1 expression could contribute to KDM4A overexpression in a substantial fraction of human prostate tumors , whereas in other prostate tumors , KDM4A can be activated by other posttranslational regulation , eg downregulation of microRNA-10 was correlated with high expression levels of KMD4A in human prostate tumors.29 Targeting USP1 promotes PC cell response to therapeutic agent enzalutamide Our above findings suggest that targeting the USP1-KDM4A axis could antagonize the growth of PC cells ."