IndraLab

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YOD1 deubiquitinates ITCH. 5 / 6
1 | 5

reach
"A recent study reported that YOD1 could deubiquitinate ITCH, and enhanced the stability of ITCH, which subsequently reduced the levels of LATS and increased the YAP/TAZ level."

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"YOD1 deubiquitinated ITCH and enhanced the stability of ITCH (shown in Figure 3)."

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"Mechanistically, YOD1 deubiquitinates ITCH, an E3 ligase of LATS, and enhances the stability of ITCH, which leads to reduced levels of LATS and a subsequent increase in the YAP and TAZ level."

reach
"Mechanistically, YOD1 deubiquitinates ITCH, an E3 ligase of LATS, and enhances the stability of ITCH, which leads to reduced levels of LATS and a subsequent increase in the YAP and TAZ level."

reach
"YOD1 regulates the Hippo signaling pathway by deubiquitinating and stabilizing ITCH (Kim et al, 2017)."