IndraLab

Statements


| 2

sparser
"These results demonstrate that the algogenic peptide ET-1 induces ET(A) receptor-mediated, hyperpolarizing shifts in the voltage-dependent activation of TTX-R Na+ channels, a potential mechanism for selective excitation by ET-1 of nociceptors that we observed in vivo."

sparser
"In companion "whole-cell" voltage-clamp experiments on canine B cells, the underlying Na+ current displays steep voltage-dependent activation and inactivation over the range of -50 to -40 mV."