IndraLab

Statements

TNFAIP3 deubiquitinates MAP3K5. 3 / 4
1 | 3
reach
"In screening for proteins that interact with ASK1 in the context of NASH, we identified the deubiquitinase tumor necrosis factor alpha induced protein 3 (TNFAIP3) as a key endogenous suppressor of ASK1 activation, and we found that TNFAIP3 directly interacts with and deubiquitinates ASK1 in hepatocytes."
29227477
reach
"The deubiquitinating enzyme tumor necrosis factor-alpha-induced protein 3 (TNFAIP3) directly interacts with and deubiquitinates ASK1 in hepatocytes and ameliorates metabolic stress-induced hepatic inflammation and fibrosis (144)."
34746195
reach
"Moreover, TNF-alpha-induced protein 3 (TNFAIP3) promotes the deubiquitination of ASK1 in hepatocytes with an anti-inflammatory effect [250]."
35563210