IndraLab

Statements

Pyraclofos inhibits KCNMA1. 5 / 5
| 5
reach
"In order to evaluate the effect of the MaxiK siRNA on voltage sensitive Ca 2+ channels currents, cells treated with siRNA were voltage clamped 48 hours after silencing and compared with mock transfected control."
21269393
reach
"KCa1.1 channel activation was closely aligned with Cav3 calcium conductance in that KCa1.1 current shared the same low voltage dependence of Cav3 activation, and was blocked by voltage dependent inactivation of Cav3 channels or by coexpressing a non calcium conducting Cav3 channel pore mutant."
23626738
reach
"It is concluded that inhibition of voltage gated as well as calcium activated (Slo) potassium channels leads to activation of gene transcription in striatal neurons which may trigger long-term changes in transmitter plasticity."
11026470
reach
"Coupling and cooperativity in voltage activation of a limited-state BK channel gating in saturating Ca 2+."
20421372
reach
"Once sufficient activation of KCa1.1 was achieved, Cav3 calcium influx left shifted the voltage dependence of KCa1.1 activation, with additional evidence for voltage dependent inactivation of KCa1.1, as expected for steady-state inactivation properties of Cav3 channels."
24413887