IndraLab

Statements

USP14 binds YTHDF1. 4 / 4
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sparser
"Based on the Co-IP assay, YTHDF1 protein was not bound to USP14 protein in BGC-823 cells ( xref )."
33791305
sparser
"To confirm the binding of USP14 mRNA with YTHDF1 protein, a RNA pull down assay was performed in BGC-823 cells using a biotinylated USP14 probe and showed that YTHDF1 was abundantly pulled down by the biotin-coupled USP14 probe rather than the control probe in BGC-823 cells ( xref )."
33791305
sparser
"These data illustrated that YTHDF1 could directly bind with USP14 mRNA and facilitated its protein translation in a m 6 A-dependent manner."
33791305
sparser
"Based on our findings and the above research reports, we believe that the YTHDF1-USP14 expression mechanism has important significance in GC development, and should be forward investigated for GC prognosis, treatment or diagnosis."
33791305