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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

SCN5A binds PGR. 1 / 1

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"Examining transcripts from human atria (n=369 samples), ventricle (n=313 samples) and other tissues, we found no evidence that SCN5A transcript expression is associated with the PR and QRS index SNPs identified in the current study (rs10428132 or rs6599251), nor with the most significant SCN10A SNPs from prior studies of PR or QRS, including rs6801957 ( xref , xref , and xref ). xref , xref While we found expression of Nav1.8 channel protein in freshly obtained human atrial tissues using immunohistochemistry ( xref ), expression of SCN10A transcript was low in atrial and ventricular tissue, therefore hampering our ability to identify a SNP SCN10A eQTL association."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...